Two types of transplant
- Autologous: the patient's own stem cells are collected, high-dose treatment is given, and the cells are returned to rebuild the bone marrow. Often used for multiple myeloma and some lymphomas.
- Allogeneic: stem cells come from a donor, such as a brother or sister, an unrelated donor, or increasingly a half-matched family member. Often considered for higher-risk leukaemias, or leukaemia that has returned.
Not every patient needs a transplant
Many people, including most children with ALL, are cured without one. A transplant carries significant risks, so it is recommended only when the expected benefit outweighs them. Dr. Haritha reviews the type of disease, its genetic risk, the response to treatment and the person's fitness before advising one.
Newer cellular therapies
For eligible blood cancer patients, Dr. Haritha also provides evaluation and referral for CAR-T cell therapy.
Common questions
Is the transplant itself an operation?
No. The stem cells are given through a drip, much like a blood transfusion. The intensive part is the high-dose treatment before it, and the recovery period while new blood cells grow.
Does every leukaemia or myeloma patient need a transplant?
No. Many are treated effectively without one. A transplant is recommended for selected patients, based on the disease, its risk features, the response to treatment and overall fitness.
Where can transplant be done?
C.R. Reddy Cancer Center in Nellore has a dedicated 4-bed transplant unit for autologous and allogeneic transplants, so families can stay close to home.
